Thrombomodulin anticorps (FITC)

N° du produit ABIN7540416

L’anticorps Souris Monoclonal anti-Thrombomodulin a été validé pour FACS. Il convient pour détecter Thrombomodulin dans des échantillons de Humain.

Aperçu rapide pour Thrombomodulin anticorps (FITC) (ABIN7540416)

Antigène: Thrombomodulin (THBD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thrombomodulin est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: M80

Détail du produit anti-Thrombomodulin anticorps (FITC)

Fonction: Anti-Hu CD141 FITC

Specificité: The mouse monoclonal antibody M80 recognizes an extracellular epitope of CD141, a 75 kDa transmembrane glycoprotein expressed mainly on macrophages, monocytes, platelets and endothelial cells.

Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: MV4-11 cell line

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur Thrombomodulin

Antigène: Thrombomodulin (THBD)

Autre désignation: CD141

Sujet:

NCBI Full Gene Name: thrombomodulin

Description: CD141, also known as thrombomodulin or fetomodulin, is a single chain type I transmembrane glycoprotein serving as a receptor for thrombin and as an important cofactor in the protein C anticoagulant system, but it is also involved in embryonic and atherosclerotic plaque development. CD141 is expressed mainly on macrophages, monocytes, a subpopulation of myeloid dendritic cells, on platelets and endothelial cells, but also e.g. on keratinocytes (epithelium). After binding to thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. Mutations in the CD141 gene can cause a thromboembolic disease known as inherited thrombophilia.

Other names: Thrombomodulin, fetomodulin, THBD, THRM, THPH12, TM

Gene name: THBD

ID gène: 7056

UniProt: P07204